| Date | Location | Result | |
| May 27, 2022 | Stillwater, Okla. | Oklahoma State 5, Clemson 1 | Box score |
| May 26, 2022 | Stillwater, Okla. | Oklahoma State 2, Clemson 0 | Box score |
| May 22, 2022 | Clemson, S.C. | Clemson 8, Louisiana 0 | Box score |
| May 21, 2022 | Clemson, S.C. | Clemson 1, Auburn 0 | Box score |
| May 20, 2022 | Clemson, S.C. | Clemson 9, UNC Wilmington 0 | Box score |
| May 14, 2022 | Pittsburgh, Pa. | Florida State 8, Clemson 6 | Box score |
| May 13, 2022 | Pittsburgh, Pa. | Clemson 4, Virginia Tech 1 | Box score |
| May 12, 2022 | Pittsburgh, Pa. | Clemson 7, Notre Dame 3 | Box score |
| May 1, 2022 | Clemson, S.C. | Clemson 3, Georgia Tech 2 | Box score |
| Apr 30, 2022 | Clemson, S.C. | Clemson 3, Georgia Tech 0 | Box score |
| Apr 29, 2022 | Clemson, S.C. | Clemson 4, Georgia Tech 1 | Box score |
| Apr 27, 2022 | Clemson, S.C. | Clemson 6, East Tennessee State 2 | Box score |
| Apr 23, 2022 | Tallahassee, Fla. | Florida State 6, Clemson 0 | Box score |
| Apr 22, 2022 | Tallahassee, Fla. | Florida State 7, Clemson 6 | Box score |
| Apr 21, 2022 | Tallahassee, Fla. | Florida State 5, Clemson 4 | Box score |
| Apr 16, 2022 | Clemson, S.C. | Clemson 2, Notre Dame 1 | Box score |
| Apr 15, 2022 | Clemson, S.C. | Notre Dame 4, Clemson 0 | Box score |
| Apr 14, 2022 | Clemson, S.C. | Clemson 3, Notre Dame 2 | Box score |
| Apr 12, 2022 | Columbia, S.C. | Clemson 3, South Carolina 1 | Box score |
| Apr 10, 2022 | Pittsburgh, Pa. | Clemson 11, Pittsburgh 3 | Box score |
| Apr 09, 2022 | Pittsburgh, Pa. | Clemson 6, Pittsburgh 5 | Box score |
| Apr 08, 2022 | Pittsburgh, Pa. | Clemson 8, Pittsburgh 0 | Box score |
| Apr 06, 2022 | Clemson, S.C. | Clemson 8, Furman 0 | Box score |
| Apr 06, 2022 | Clemson, S.C. | Clemson 3, Furman 2 | Box score |
| Apr 03, 2022 | Chapel Hill | Clemson 12, North Carolina 4 | Box score |
| Apr 02, 2022 | Chapel Hill | Clemson 7, North Carolina 0 | Box score |
| Apr 01, 2022 | Chapel Hill | Clemson 12, North Carolina 4 | Box score |
| Mar 30, 2022 | Clemson, S.C. | Clemson 8, South Carolina 1 | Box score |
| Mar 27, 2022 | Clemson, S.C. | Louisville 4, Clemson 2 | Box score |
| Mar 26, 2022 | Clemson, S.C. | Clemson 8, Louisville 0 | Box score |
| Mar 25, 2022 | Clemson, S.C. | Clemson 5, Louisville 2 | Box score |
| Mar 23, 2022 | Athens, Ga. | Georgia 3, Clemson 2 | Box score |
| Mar 20, 2022 | Durham, N.C. | Duke 7, Clemson 1 | Box score |
| Mar 19, 2022 | Durham, N.C. | Clemson 10, Duke 2 | Box score |
| Mar 18, 2022 | Durham, N.C. | Duke 6, Clemson 2 | Box score |
| Mar 15, 2022 | Clemson, S.C. | Clemson 8, Winthrop 0 | Box score |
| Mar 14, 2022 | Clemson, S.C. | Clemson 1, Liberty 0 | Box score |
| Mar 13, 2022 | Clemson, S.C. | Clemson 5, Liberty 4 | Box score |
| Mar 13, 2022 | Clemson, S.C. | Clemson 4, Illinois 0 | Box score |
| Mar 12, 2022 | Clemson, S.C. | Clemson 3, Illinois 1 | Box score |
| Mar 09, 2022 | Clemson, S.C. | Clemson 3, Mercer 0 | Box score |
| Mar 06, 2022 | Clemson, S.C. | Virginia Tech 4, Clemson 2 | Box score |
| Mar 05, 2022 | Clemson, S.C. | Virginia Tech 4, Clemson 0 | Box score |
| Mar 04, 2022 | Clemson, S.C. | Virginia Tech 6, Clemson 1 | Box score |
| Mar 01, 2022 | Clemson, S.C. | Clemson 6, Gardner-Webb 0 | Box score |
| Feb 26, 2022 | Clemson, SC | Clemson 7, Boston University 3 | Box score |
| Feb 26, 2022 | Clemson, SC | Clemson 10, Akron 5 | Box score |
| Feb 25, 2022 | Clemson, SC | Clemson 2, St. Francis 0 | Box score |
| Feb 25, 2022 | Clemson, SC | Clemson 8, Boston University 0 | Box score |
| Feb 23, 2022 | Charlotte, N.C. | Clemson 5, Charlotte 2 | Box score |
| Feb 20, 2022 | Clearwater, Fla. | Clemson 2, Washington 0 | Box score |
| Feb 19, 2022 | Clearwater, Fla. | Wisconsin 2, Clemson 1 | Box score |
| Feb 19, 2022 | Clearwater, Fla. | Northwestern 7, Clemson 0 | Box score |
| Feb 18, 2022 | Clearwater, Fla. | Clemson 4, Tennessee 3 | Box score |
| Feb 17, 2022 | Clearwater, Fla. | Clemson 8, Texas Tech 0 | Box score |
| Feb 12, 2022 | Fort Myers, Fla. | Clemson 8, LIU 0 | Box score |
| Feb 11, 2022 | Fort Myers, Fla. | Texas 4, Clemson 0 | Box score |
| Feb 11, 2022 | Fort Myers, Fla. | Clemson 8, Kent St. 0 | Box score |
| Feb 10, 2022 | Fort Myers, Fla. | Clemson 11, FGCU 0 | Box score |