| Date | Location | Result | |
| May 16, 2021 | Tallahassee, Fla. | Florida State 9, Clemson 6 | Box score |
| May 15, 2021 | Tallahassee, Fla. | Clemson 9, Florida State 5 | Box score |
| May 14, 2021 | Tallahassee, Fla. | Florida State 8, Clemson 3 | Box score |
| May 11, 2021 | Clemson, S.C. | Clemson 7, South Carolina 2 | Box score |
| May 09, 2021 | Atlanta, Ga. | Georgia Tech 9, Clemson 8 | Box score |
| May 08, 2021 | Atlanta, Ga. | Georgia Tech 6, Clemson 5 | Box score |
| May 07, 2021 | Atlanta, Ga. | Georgia Tech 6, Clemson 1 | Box score |
| May 05, 2021 | Clemson, S.C. | Clemson 9, USC Upstate 2 | Box score |
| May 02, 2021 | Clemson, S.C. | Clemson 15, Louisville 5 | Box score |
| May 01, 2021 | Clemson, S.C. | Clemson 5, Louisville 4 | Box score |
| Apr 30, 2021 | Clemson, S.C. | Clemson 11, Louisville 3 | Box score |
| Apr 25, 2021 | Clemson, S.C. | Clemson 3, Wake Forest 2 | Box score |
| Apr 25, 2021 | Clemson, S.C. | Clemson 6, Wake Forest 4 | Box score |
| Apr 23, 2021 | Clemson, S.C. | Clemson 5, Wake Forest 2 | Box score |
| Apr 20, 2021 | Athens, Ga. | Georgia 8, Clemson 7 | Box score |
| Apr 18, 2021 | Coral Gables, Fla. | Miami (Fla.) 3, Clemson 2 | Box score |
| Apr 17, 2021 | Coral Gables, Fla. | Miami (Fla.) 10, Clemson 2 | Box score |
| Apr 16, 2021 | Coral Gables, Fla. | Miami (Fla.) 12, Clemson 3 | Box score |
| Apr 13, 2021 | Clemson, S.C. | Coll. of Charleston 13, Clemson 6 | Box score |
| Apr 11, 2021 | Clemson, S.C. | Virginia 6, Clemson 5 | Box score |
| Apr 10, 2021 | Clemson, S.C. | Virginia 8, Clemson 4 | Box score |
| Apr 09, 2021 | Clemson, S.C. | Clemson 6, Virginia 1 | Box score |
| Apr 04, 2021 | Raleigh, N.C. | NC State 9, Clemson 5 | Box score |
| Apr 03, 2021 | Raleigh, N.C. | Clemson 9, NC State 3 | Box score |
| Apr 02, 2021 | Raleigh, N.C. | Clemson 10, NC State 6 | Box score |
| Mar 30, 2021 | Clemson, S.C. | Georgia 2, Clemson 0 | Box score |
| Mar 27, 2021 | Brighton, Mass. | Clemson 7, Boston College 2 | Box score |
| Mar 27, 2021 | Brighton, Mass. | Clemson 9, Boston College 3 | Box score |
| Mar 26, 2021 | Brighton, Mass. | Clemson 16, Boston College 12 | Box score |
| Mar 23, 2021 | North Augusta, S.C. | Clemson 6, Georgia Southern 4 | Box score |
| Mar 21, 2021 | Clemson, S.C. | Clemson 4, Virginia Tech 2 | Box score |
| Mar 20, 2021 | Clemson, S.C. | Virginia Tech 11, Clemson 3 | Box score |
| Mar 19, 2021 | Clemson, S.C. | Clemson 8, Virginia Tech 2 | Box score |
| Mar 16, 2021 | Clemson, S.C. | Clemson 7, Georgia State 2 | Box score |
| Mar 14, 2021 | Chapel Hill, N.C. | North Carolina 5, Clemson 3 | Box score |
| Mar 13, 2021 | Chapel Hill, N.C. | North Carolina 5, Clemson 4 | Box score |
| Mar 12, 2021 | Chapel Hill, N.C. | North Carolina 8, Clemson 3 | Box score |
| Mar 09, 2021 | Clemson, S.C. | USC Upstate 12, Clemson 2 | Box score |
| Mar 07, 2021 | Clemson, S.C. | Notre Dame 3, Clemson 2 | Box score |
| Mar 06, 2021 | Clemson, S.C. | Notre Dame 3, Clemson 1 | Box score |
| Mar 05, 2021 | Clemson, S.C. | Clemson 13, Notre Dame 7 | Box score |
| Mar 02, 2021 | Clemson, S.C. | Clemson 7, East Tennessee State 3 | Box score |
| Feb 28, 2021 | Columbia, S.C. | South Carolina 8, Clemson 7 | Box score |
| Feb 27, 2021 | Greenville, S.C. | South Carolina 3, Clemson 2 | Box score |
| Feb 21, 2021 | Clemson, S.C. | Clemson 8, Cincinnati 7 | Box score |
| Feb 20, 2021 | Clemson, S.C. | Clemson 5, Cincinnati 2 | Box score |
| Feb 19, 2021 | Clemson, S.C. | Clemson 5, Cincinnati 0 | Box score |